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Article

Genetic variability of hepatitis B virus in acute and in different phases of chronic infection in Brazil.

Scientific reports - 10 May 2024

Lago Barbara Vieira, Portilho Moyra Machado, Mello Vinicius Motta, De Sousa Paulo Sergio Fonseca, Angelice Giovana Paula, Marques Bianca Cristina Leires, da Silva Andrade Larissa Tropiano, Marques Vanessa Alves, Lewis-Ximenez Lia Laura, Mello Francisco Campello do Amaral, Villar Livia Melo

Abstract excerpt

The selection pressure imposed by the host immune system impacts on hepatitis B virus (HBV) variability. This study evaluates HBV genetic diversity, nucleos(t)ide analogs resistance and HBsAg escape mutations in HBV patients under distinct selective pressures. One hundred and thirteen individuals in different phases of HBV infection were included: 13 HBeAg-positive chronic infection, 9 HBeAg-positive chronic...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38730249
DOI: 10.1038/s41598-024-60900-2
PMCID: PMC11087654

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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