Article
The replication and transcription activator of murine gammaherpesvirus 68 cooperatively enhances cytokine-activated, STAT3-mediated gene expression.
The Journal of biological chemistry - 29 Sept 2017
Foreman Hui-Chen Chang, Armstrong Julie, Santana Alexis L, Krug Laurie T, Reich Nancy C
Abstract excerpt
Gammaherpesviruses (γHVs) have a dynamic strategy for lifelong persistence, involving productive infection, latency, and intermittent reactivation. In latency reservoirs, such as B lymphocytes, γHVs exist as viral episomes and express few viral genes. Although the ability of γHV to reactivate from latency and re-enter the lytic phase is challenging to investigate and control, it is known that the γHV replication...
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