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Article

Necrotizing enterocolitis and high intestinal iron uptake due to genetic variants.

Pediatric research - 1 Jan 2018

Göpel Wolfgang, Drese Josephine, Rausch Tanja K, Twisselmann Nele, Bohnhorst Bettina, Müller Andreas, Franz Axel, Ziegler Andreas, Härtel Christoph, Herting Egbert

Abstract excerpt

BackgroundIntestinal iron is a nutritional compound, which is essential for enteric microbiota. We evaluated the hypothesis that polymorphisms, which are known modifiers of intestinal iron uptake in adults, are associated with necrotizing enterocolitis (NEC) in preterm infants.MethodsPreterm infants (birth weight below 1,500 g) were studied. Single-nucleotide polymorphisms with known effects on serum iron levels...

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PMID: 28820869
DOI: 10.1038/pr.2017.195

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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