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Article

Effect on gene expression of three allelic variants in GATA motifs of ABO, RHD, and RHCE regulatory elements.

Transfusion - 1 Nov 2017

Fennell Katie, Hoffman Roser, Yoshida Ken, Iwamoto Sadahiko, Govender Lavendri, Vather Kuben, Sookraj Ashika, Jentsch Ute, Pambrun Chantale, McAuley Catherine, Keller Margaret A, Ochoa-Garay Gorka

Abstract excerpt

BACKGROUND: Only a few genetic variants have been reported in regulatory elements of blood group genes. Most of them affect GATA motifs, binding sites for the GATA-1 transcription factor. STUDY DESIGN AND METHODS: Samples from two patients and one donor with unusual or discrepant serology for ABO, RhD, and RhCE antigens were analyzed by DNA sequencing. Analyzed regions included the coding sequence and portions of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Regulatory Sequences, Nucleic Acid

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Source

Identifiers

PMID: 28815618
DOI: 10.1111/trf.14299

Genes

RHCE
ABO
RHD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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