Article
Molecular genetic analysis of ABO blood group variations reveals 29 novel ABO subgroup alleles.
Transfusion - 1 Nov 2013
Cai Xiaohong, Jin Sha, Liu Xi, Fan Liangfeng, Lu Qiong, Wang Jianlian, Shen Wei, Gong Songsong, Qiu Li, Xiang Dong
Abstract excerpt
BACKGROUND: Identifying genetic variants of the ABO gene may reveal new biologic mechanisms underlying variant phenotypes of the ABO blood group. We report the molecular genetic analysis of 322 apparently unrelated ABO subgroup individuals in an estimated 2.1 million donors. STUDY DESIGN AND METHODS: We performed phenotype investigations by serology studies, analyzed the DNA sequence of the ABO gene by direct...
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