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Article

The polymorphism of ABO gene regulatory regions in 120 individuals residing in Dalian, China.

Transfusion medicine (Oxford, England) - 1 Aug 2026

Shao Lin-Nan, Xia Yue-Xin, Yang Yi-Cheng, Li Ning, Li Chun-Xiang, Wang Li-Ying, Song Wen-Qian, Zhou Shi-Hang, Fan Ya-Xin

Abstract excerpt

BACKGROUND: The ABO gene encodes glycosyltransferase A and B enzymes. Reduced enzyme activity is primarily caused by variations in the coding region and splicing sites. Additionally, variations in regulatory regions like the CCAAT binding factor (CBF)/NF-Y binding site, proximal promoter, and + 5.8-kb site may also diminish enzyme activities. OBJECTIVE: This study enrolled 120 Chinese individuals (111 with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Regulatory Sequences, Nucleic Acid

Source

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Identifiers

PMID: 41591327
DOI: 10.1111/tme.70066
PMCID: PMC13475295

Genes

ABO
RUNX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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