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Article

Genetic Features of HIV-1 Integrase Sub-Subtype A6 Predominant in Russia and Predicted Susceptibility to INSTIs.

Viruses - 31 Jul 2020

Kirichenko Alina, Lapovok Ilya, Baryshev Pavel, van de Vijver David A M C, van Kampen Jeroen J A, Boucher Charles A B, Paraskevis Dimitrios, Kireev Dmitry

Abstract excerpt

The increasing use of the integrase strand transfer inhibitor (INSTI) class for the treatment of HIV-infection has pointed to the importance of analyzing the features of HIV-1 subtypes for an improved understanding of viral genetic variability in the occurrence of drug resistance (DR). In this study, we have described the prevalence of INSTI DR in a Russian cohort and the genetic features of HIV-1 integrase...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32752001
DOI: 10.3390/v12080838
PMCID: PMC7472261

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