Article

In silico and in vitro analysis of recombinant arginine deiminase from Pseudomonas furukawaii as a potential anticancer enzyme

2022-01-21

Abstract excerpt

<title>Abstract</title> Arginine deiminase (ADI), a promising anticancer enzyme from <italic>Mycoplasma hominis, </italic>is currently in phase III of clinical trials for the treatment of arginine auxotrophic tumors. However, it has been associated with several drawbacks in terms of low stability at human physiological conditions, high immunogenicity, hypersensitivity and systemic toxicity. In our previous wor...

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Literature Corpus work: 90eef57c-b4fe-5637-b4a4-44f904bbdbfb
DOI: 10.21203/rs.3.rs-1000203/v3

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