Anti-EDAR Agonist Antibody Therapy Resolves Palate Defects in Pax9-/- Mice.

Abstract excerpt

To date, surgical interventions are the only means by which craniofacial anomalies can be corrected so that function, esthetics, and the sense of well-being are restored in affected individuals. Unfortunately, for patients with cleft palate-one of the most common of congenital birth defects-treatment following surgery is prolonged over a lifetime and often involves multidisciplinary regimens. Hence, there is a...

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