Article
Low levels of genetic diversity associated with evidence of negative selection on the Babesia bovis apical membrane antigen 1 from parasite populations in Thailand.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Oct 2017
Rittipornlertrak Amarin, Nambooppha Boondarika, Simking Pacharathon, Punyapornwithaya Veerasak, Tiwananthagorn Saruda, Jittapalapong Sathaporn, Chung Yang-Tsung, Sthitmatee Nattawooti
Abstract excerpt
Babesia bovis, a parasite infecting cattle and buffalo, continues to spread throughout the developing world. The babesial vaccine was developed to be a sustainable alternative treatment to control the parasite. However, genetic diversity is a major obstacle for designing and developing a safe and effective vaccine. The apical membrane antigen 1 (AMA-1) is considered to be a potential vaccine candidate antigen...
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