Diversity and population genetic analysis of the Babesia bovis merozoite surface Antigen 1 (MSA-1) gene in South African cattle isolates from field and clinical samples.

doi:10.1016/j.vetpar.2026.110862

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Diversity and population genetic analysis of the Babesia bovis merozoite surface Antigen 1 (MSA-1) gene in South African cattle isolates from field and clinical samples.

Veterinary parasitology - 1 Oct 2026

Bambeni Thandikhaya, Schnittger Leonhard, Bhoora Raksha Vasantrai

Abstract excerpt

Babesia bovis causes significant losses in South African cattle, and antigenic variation in the merozoite surface antigen 1 (msa-1) complicates vaccine and diagnostic development. This study provides the first detailed molecular characterisation of msa-1 genetic diversity in South African cattle populations. Analysis of 18 successfully sequenced isolates (∼960 bp) revealed extensive polymorphism, with pairwise...

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Topics

Animals
Cattle
Babesia bovis
South Africa
Genetic Variation
Phylogeny

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Babesiosis

Merozoite Surface Protein 1

Cattle Diseases

Haplotypes

Polymorphism, Genetic

Antigens, Protozoan

Amino Acid Sequence

Source

Open in PubMed

Identifiers

PMID: 42480497
DOI: 10.1016/j.vetpar.2026.110862

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