Article
Genetic Diversity of Merozoite Surface Antigens in Global Babesia bovis Populations.
Genes - 13 Oct 2023
El-Alfy El-Sayed, Abbas Ibrahim, Elseadawy Rana, El-Sayed Shimaa Abd El-Salam, Rizk Mohamed Abdo
Abstract excerpt
Cattle can be severely infected with the tick-borne protozoa Babesia bovis, giving rise to serious economic losses. Invasion of the host's RBCs by the parasite merozoite/sporozoites depends largely on the MSA (merozoite surface antigens) gene family, which comprises various fragments, e.g., MSA-1, MSA-2a1, MSA-2a2, MSA-2b and MSA-2c, highlighting the importance of these antigens as vaccine candidates. However,...
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