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The regulatory role of long non- coding RNAs as a novel controller of immune response against cancer cells

7 Oct 2022

Abstract excerpt

Immunotherapy has been established as a promising therapy for different cancer types. However, many patients experience primary or secondary resistance to treatment. Immune cells and anti-inflammatory factors are regulated by long noncoding RNAs (lncRNAs). In addition, lncRNAs have a role in immune resistance through antigen presentation loss or attenuation, PD-L1 upregulation, loss of T-cell activities, and...

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PMID: 36207500
DOI: 10.1007/s11033-022-07947-4

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