Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

lysX gene is differentially expressed among Mycobacterium tuberculosis strains with different levels of virulence.

Tuberculosis (Edinburgh, Scotland) - 1 Sept 2017

Montoya-Rosales Alejandra, Provvedi Roberta, Torres-Juarez Flor, Enciso-Moreno Jose A, Hernandez-Pando Rogelio, Manganelli Riccardo, Rivas-Santiago Bruno

Abstract excerpt

Antimicrobial peptides (AMPs) are mainly produced by epithelial cells and macrophages to eliminate infecting mycobacteria through direct antimicrobial activity and immunomodulation. Indeed, it has been described that this line of defense is essential to control infection. However, Mycobacterium tuberculosis (Mtb) has developed mechanisms to avoid AMPs activity, for instance lysX adds lysine residues to surface...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to A549 Cells
Share to Antimicrobial Cationic Peptides

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Antitubercular Agents

Share to beta-Defensins

Share to Cathelicidins

Share to Host-Pathogen Interactions

Share to Phagocytosis

Share to Tuberculosis, Pulmonary

Source

Identifiers

PMID: 28802397
DOI: 10.1016/j.tube.2017.07.005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

lysX gene is differentially expressed among Mycobacterium tuberculosis strains with different levels of virulence.PMID 28802397Read ↗

Unveiling the Significance of LysE in Survival and Virulence of Mycobacterium Tuberculosis: A Comprehensive Review reveals it as a potential Drug Target, Diagnostic Marker, and a Vaccine CandidateSemantic proximity Read ↗

Mutation on lysX from Mycobacterium avium hominissuis impacts the host-pathogen interaction and virulence phenotype.Semantic proximity Read ↗

The two-domain LysX protein of Mycobacterium tuberculosis is required for production of lysinylated phosphatidylglycerol and resistance to cationic antimicrobial peptides.Semantic proximity Read ↗

A Small Protein but with Diverse Roles: A Review of EsxA in Mycobacterium–Host InteractionSemantic proximity Read ↗

PE11, a PE/PPE family protein of Mycobacterium tuberculosis is involved in cell wall remodeling and virulenceSemantic proximity Read ↗

Interaction of Mycobacteria With Host Cell InflammasomesSemantic proximity Read ↗

To Be or Not to Be a Pseudogene: A Molecular Epidemiological Approach to the mclx Genes and Its Impact in Tuberculosis.Semantic proximity Read ↗

Identification of genes required for Mycobacterium abscessus growth in vivo with a prominent role of the ESX-4 locus.Semantic proximity Read ↗

Conserved ESX-1 Substrates EspE and EspF Are Virulence Factors That Regulate Gene ExpressionSemantic proximity Read ↗

Mycobacterial Secretion Systems ESX-1 and ESX-5 Play Distinct Roles in Host Cell Death and Inflammasome ActivationSemantic proximity Read ↗

Roles of Lipolytic enzymes in Mycobacterium tuberculosis pathogenesisSemantic proximity Read ↗

Differential fadE28 expression associated with phenotypic virulence of Mycobacterium tuberculosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.