Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutation on lysX from Mycobacterium avium hominissuis impacts the host-pathogen interaction and virulence phenotype.

Virulence - 1 Dec 2020

Kirubakar Greana, Schäfer Hubert, Rickerts Volker, Schwarz Carsten, Lewin Astrid

Abstract excerpt

The lysX gene from Mycobacterium avium hominissuis (MAH) is not only involved in cationic antimicrobial resistance but also regulates metabolic activity. An MAH lysX deficient mutant was shown to exhibit a metabolic shift at the extracellular state preadapting the bacteria to the conditions inside host-cells. It further showed stronger growth in human monocytes. In the present study, the LysX activity on...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Proteins
Share to Cell Line
Share to Host-Pathogen Interactions

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Macrophages

Share to Mycobacterium avium

Share to Virulence

Source

Open in PubMed Open full text

Identifiers

PMID: 31996090
DOI: 10.1080/21505594.2020.1713690
PMCID: PMC6999840

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutation on lysX from Mycobacterium avium hominissuis impacts the host-pathogen interaction and virulence phenotype.PMID 31996090Read ↗

lysX gene is differentially expressed among Mycobacterium tuberculosis strains with different levels of virulence.Semantic proximity Read ↗

<i>Stenotrophomonas muris</i>- First discovered as an urgent human pathogen with strong virulence associated with bloodstream infectionsSemantic proximity Read ↗

Unraveling the adaptive strategies of Mycoplasma hominis through proteogenomic profiling of clinical isolates.Semantic proximity Read ↗

Mycobacterium avium Subsp. hominissuis Interactions with Macrophage Killing MechanismsSemantic proximity Read ↗

Physiological, genetical and morphological alterations in Mycobacterium avium subsp. paratuberculosis mutants generated with the CRISPRi system.Semantic proximity Read ↗

Virulence Effectors of Pathogenic MycoplasmasSemantic proximity Read ↗

Host-pathogen interactions in mycoplasma pathogenesis: Virulence and survival strategies of minimalist prokaryotesSemantic proximity Read ↗

Virulence-related Mycobacterium avium subsp hominissuis MAV_2928 gene is associated with vacuole remodeling in macrophagesSemantic proximity Read ↗

Managing Manganese: The Role of Manganese Homeostasis in Streptococcal PathogenesisSemantic proximity Read ↗

The Endospore-Forming Pathogen Bacillus cereus Exploits a Small Colony Variant-Based Diversification Strategy in Response to Aminoglycoside Exposure.Semantic proximity Read ↗

Functional Characterization of the N-Acetylmuramyl-l-Alanine Amidase, Ami1, from Mycobacterium abscessus.Semantic proximity Read ↗

Mycobacterium avium ssp. hominissuis biofilm is composed of distinct phenotypes and influenced by the presence of antimicrobials.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.