Article
Lack of association between the P413L variant of chromogranin B and ALS risk or age at onset: a meta-analysis.
Amyotrophic lateral sclerosis & frontotemporal degeneration - 1 Feb 2018
Yang Xinglong, Li Shimei, Xing Dongmei, Li Peiyun, Li Ci, Qi Ling, Xu Yanming, Ren Hui
Abstract excerpt
BACKGROUND: Amyotrophic lateral sclerosis (ALS), the most common motor neuron disease, is thought to result from interaction of genetic and environmental risk factors. Whether the potentially functional exonic P413L variant in the chromogranin B gene influences ALS risk and age at onset is controversial. METHOD: We meta-analysed or other studies assessing the association between the P413L variant and ALS risk or...
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