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Article

The P413L chromogranin B variation in French patients with sporadic amyotrophic lateral sclerosis.

Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases - 1 May 2011

Blasco Hélène, Corcia Philippe, Veyrat-Durebex Charlotte, Coutadeur Cathleen, Fournier Clémentine, Camu William, Gordon Paul, Praline Julien, Andres Christian R, Vourc'h Patrick

Abstract excerpt

Chromogranins interact with mutant forms of superoxide dismutase 1 (SOD1) responsible for a portion of familial amyotrophic lateral sclerosis (ALS). A particular variation (P413L) in the chromogranin B gene, CHGB, has been recently associated with an earlier age at onset in both familial and sporadic ALS. The aim of our study was to evaluate the P413L chromogranin variation in French patients with sporadic...

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Source

Identifiers

PMID: 20932227
DOI: 10.3109/17482968.2010.522587

Genes

CHGB
SOD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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