Article
Chromogranin B P413L variant as risk factor and modifier of disease onset for amyotrophic lateral sclerosis.
Proceedings of the National Academy of Sciences of the United States of America - 22 Dec 2009
Gros-Louis Francois, Andersen Peter M, Dupre Nicolas, Urushitani Makoto, Dion Patrick, Souchon Frederique, D'Amour Monique, Camu William, Meininger Vincent, Bouchard Jean-Pierre, Rouleau Guy A, Julien Jean-Pierre
Abstract excerpt
Recently, chromogranins were reported to interact specifically with mutant forms of superoxide dismutase that are linked to amyotrophic lateral sclerosis (ALS). This interaction led us to analyze the frequencies of sequence variants of the CHGB gene in ALS patients and matched controls from three...
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