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Article

NKG2D gene polymorphisms are associated with disease control of chronic myeloid leukemia by dasatinib.

International journal of hematology - 1 Nov 2017

Hara Ryujiro, Onizuka Makoto, Matsusita Erika, Kikkawa Eri, Nakamura Yoshihiko, Matsushita Hiromichi, Ohgiya Daisuke, Murayama Hiromichi, Machida Shinichiro, Ohmachi Ken, Shirasugi Yukari, Ogawa Yoshiaki, Kawada Hiroshi, Ando Kiyoshi

Abstract excerpt

A recent study reported that treatment-free remission (TFR) of chronic myeloid leukemia (CML) after dasatinib (Das) treatment was significantly associated with natural killer (NK) cell proliferation in the peripheral blood. However, biomarkers to predict lymphocytosis or successful TFR are not well characterized. In order to clarify individual differences in NK cell responses among patients treated with Das, we...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chronic Myeloid Leukemia Treatments

Share to Dasatinib

Share to Leukemia, Myelogenous, Chronic, BCR-ABL Positive

Share to Neoplasm Proteins

Share to NK Cell Lectin-Like Receptor Subfamily K

Share to Polymorphism, Genetic

Source

Identifiers

PMID: 28795321
DOI: 10.1007/s12185-017-2294-1

Genes

KLRK1
VAV1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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