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Maternal Western diet age‐specifically alters female offspring voluntary physical activity and dopamine‐ and leptin‐related gene expression

9 Aug 2017

Abstract excerpt

ABSTRACT Prenatal overnutrition affects development into adulthood and influences risk of obesity. We assessed the transgenerational effect of maternal Western diet (WD) consumption on offspring physical activity. Voluntary wheel running was increased in juvenile (4–7 wk ofage), but decreased in adult (16–19 wk of age), F 1 female WD offspring. In contrast, no wheel‐running differences in F 1 male offspring were...

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PMID: 28794174
DOI: 10.1096/fj.201700389r

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