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Article

A Model for Viral Assembly around an Explicit RNA Sequence Generates an Implicit Fitness Landscape.

Biophysical journal - 8 Aug 2017

Dykeman Eric Charles

Abstract excerpt

Previously, a stochastic model of single-stranded RNA virus assembly was created to model the cooperative effects between capsid proteins and genomic RNA that would occur in a packaging signal-mediated assembly process. In such an assembly scenario, multiple secondary structural elements from within the RNA, termed "packaging signals" (PS), contact coat proteins and facilitate efficient capsid assembly. In this...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28793206
DOI: 10.1016/j.bpj.2017.06.037
PMCID: PMC5550301

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