Article
Prevalence of -alpha(3.7) and alpha alpha alpha(anti3.7) alleles in sickle cell trait and beta-thalassemia patients in Mexico.
Blood cells, molecules & diseases - 1 Jan 2000
Nava María Paulina, Ibarra Bertha, Magaña María Teresa, de la Luz Chávez María, Perea F Javier
Abstract excerpt
The aim of this study was to determine the frequency of alpha-globin gene mutations in three groups of Mexican unrelated individuals. The first two groups were normal and sickle cell trait individuals from the Costa Chica region, a place with a 12.8% frequency of HbS carriers, and the third group comprised of Mexican mestizo patients with beta-thalassemia. We searched for -alpha(3.7) and -alpha(4.2)...
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