Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Complex analysis of the TP53 tumor suppressor in mantle cell and diffuse large B-cell lymphomas.

Oncology reports - 1 Oct 2017

Zlamalikova Lenka, Moulis Mojmir, Ravcukova Barbora, Liskova Kvetoslava, Malcikova Jitka, Salek David, Jarkovsky Jiri, Svitakova Miluse, Hrabalkova Renata, Smarda Jan, Smardova Jana

Abstract excerpt

Mutations and deletions of the tumor suppressor TP53 gene are the most frequent genetic alterations detected in human tumors, though they are rather less frequent in lymphomas. However, acquisition of the TP53 mutation was demonstrated to be one of the characteristic markers in mantle cell lymphoma (MCL) and diffuse large B-cell lymphoma (DLBCL) and prognostic value of the TP53 status has been recognized for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cyclophosphamide
Share to Doxorubicin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lymphoma, Large B-Cell, Diffuse

Share to Lymphoma, Mantle-Cell

Share to Prednisone

Share to Rituximab

Share to Vincristine

Share to Yeasts

Source

Identifiers

PMID: 28791403
DOI: 10.3892/or.2017.5891

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Complex analysis of the TP53 tumor suppressor in mantle cell and diffuse large B-cell lymphomas.PMID 28791403Read ↗

Loss of the p53 tumor suppressor activity is associated with negative prognosis of mantle cell lymphoma.Semantic proximity Read ↗

Prognostic impact of p53 aberrations for R-CHOP-treated patients with diffuse large B-cell lymphoma.Semantic proximity Read ↗

Progress in deciphering the role of p53 in diffuse large B-cell lymphoma: mechanisms and therapeutic targetsSemantic proximity Read ↗

A comprehensive study of TP53 mutations in chronic lymphocytic leukemia: Analysis of 1287 diagnostic and 1148 follow-up CLL samples.Semantic proximity Read ↗

Relevance of TP53 for CLL diagnosticsSemantic proximity Read ↗

TP53 mutation and survival in aggressive B cell lymphoma.Semantic proximity Read ↗

TP53 mutation heterogeneity reveals distinct prognoses in mantle cell lymphoma.Semantic proximity Read ↗

Identify truly high-risk TP53-mutated diffuse large B cell lymphoma patients and explore the underlying biological mechanisms.Semantic proximity Read ↗

TP53 mutation predict poor prognosis in diffuse large B-cell lymphoma: a single-center study.Semantic proximity Read ↗

Prognostic Impact of TP53 Mutations in Diffuse Large B-Cell LymphomaSemantic proximity Read ↗

Dysfunction of the TP53 tumor suppressor gene in lymphoid malignanciesSemantic proximity Read ↗

Mutational profile and prognostic significance of TP53 in diffuse large B-cell lymphoma patients treated with R-CHOP: report from an International DLBCL Rituximab-CHOP Consortium Program Study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.