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Article

Spleen tyrosine kinase influences the early stages of multilineage differentiation of bone marrow stromal cell lines by regulating phospholipase C gamma activities.

Journal of cellular physiology - 1 Mar 2018

Kusuyama Joji, Kamisono Ai, ChangHwan Seong, Amir Muhammad S, Bandow Kenjiro, Eiraku Nahoko, Ohnishi Tomokazu, Matsuguchi Tetsuya

Abstract excerpt

Bone marrow stromal cells (BMSCs) are multipotent cells that can differentiate into adipocytes and osteoblasts. Inadequate BMSC differentiation is occasionally implicated in chronic bone metabolic disorders. However, specific signaling pathways directing BMSC differentiation have not been elucidated. Here, we explored the roles of spleen tyrosine kinase (Syk) in BMSC differentiation into adipocytes and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28786489
DOI: 10.1002/jcp.26130

Genes

BLNK

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