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Article

Multi-polygenic score approach to trait prediction.

Molecular psychiatry - 1 May 2018

Krapohl E, Patel H, Newhouse S, Curtis C J, von Stumm S, Dale P S, Zabaneh D, Breen G, O'Reilly P F, Plomin R

Abstract excerpt

A primary goal of polygenic scores, which aggregate the effects of thousands of trait-associated DNA variants discovered in genome-wide association studies (GWASs), is to estimate individual-specific genetic propensities and predict outcomes. This is typically achieved using a single polygenic score, but here we use a multi-polygenic score (MPS) approach to increase predictive power by exploiting the joint power...

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Identifiers

PMID: 28785111
DOI: 10.1038/mp.2017.163
PMCID: PMC5681246

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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