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Article

Overview of inactivating mutations in the protein-coding genome of the mouse reference strain C57BL/6J.

JCI insight - 12 Jul 2018

Timmermans Steven, Libert Claude

Abstract excerpt

Mice are extremely important as the premier model organism in human biomedical and mammalian genetic research. The genomes of several tens of mouse inbred strains have been sequenced. They have been compared to the genome of C57BL/6J, considered by convention as the reference genome. Based on a comparison of this reference genome with 36 other sequenced mouse strains, we generated an overview of all...

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Identifiers

PMID: 29997285
DOI: 10.1172/jci.insight.121758
PMCID: PMC6124530

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