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Article

A critical role of LFA-1 in the development of Th17 cells and induction of experimental autoimmune encephalomyelytis.

Biochemical and biophysical research communications - 23 Feb 2007

Wang Yinan, Kai Hirayasu, Chang Fei, Shibata Kai, Tahara-Hanaoka Satoko, Honda Shin-ichiro, Shibuya Akira, Shibuya Kazuko

Abstract excerpt

The alphaLbeta2 integrin adhesion molecule LFA-1 is believed to be involved in the migration of autoreactive T cells to the central nervous system across the endothelial blood-brain barrier in experimental autoimmune encephalomyelitis (EAE). Here, we demonstrate that the incidence and clinical sc...

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Share to CD4 Antigens
Share to Encephalomyelitis, Autoimmune, Experimental

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interleukin-17

Share to Lymphocyte Function-Associated Antigen-1

Share to Myelin-Associated Glycoprotein

Share to Myelin-Oligodendrocyte Glycoprotein

Share to Myelin Proteins

Share to T-Lymphocytes, Helper-Inducer

Source

Identifiers

PMID: 17207459
DOI: 10.1016/j.bbrc.2006.12.104

Genes

MOG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17207459-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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