Article
Plasmid-based high-resolution melting analysis for accurate detection of rpoB mutations in Mycobacterium tuberculosis isolates from Moroccan patients.
BMC infectious diseases - 7 Aug 2017
Bentaleb El Mehdi, El Messaoudi My Driss, Abid Mohammed, Messaoudi Malika, Yetisen Ali K, Sefrioui Hassan, Amzazi Saaïd, Ait Benhassou Hassan
Abstract excerpt
BACKGROUND: Rapid diagnosis of drug resistance in tuberculosis (TB) is pivotal for the timely initiation of effective antibiotic treatment to prevent the spread of drug-resistant strains. The development of low-cost, rapid and robust methods for drug-resistant TB detection is highly desirable for resource-limited settings. METHODS: We report the use of an in house plasmid-based quantitative polymerase chain...
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