Article
Molecular characterisation of rifampicin-resistant Mycobacterium tuberculosis strains from Morocco.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease - 1 Nov 2009
Kourout M, Chaoui I, Sabouni R, Lahlou O, El Mzibri M, Jordaan A, Victor T C, Akrim M, El Aouad R
Abstract excerpt
Mutations in the rpoB gene associated with rifampicin (RMP) resistance were studied in 47 RMP-resistant and 147 RMP-susceptible clinical strains of Mycobacterium tuberculosis from Morocco using probe-based assay and DNA sequencing. RMP-resistant mutations were identified in 85% of RMP-resistant isolates. No mutations were observed among the 147 RMP-susceptible strains. Sequence analysis identified 10 alleles,...
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