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Article

Next generation sequencing of carcinoma of unknown primary reveals novel combinatorial strategies in a heterogeneous mutational landscape

23 Jun 2017

Abstract excerpt

Background: Advanced carcinoma of unknown primary (CUP) has limited effective therapeutic options given the phenotypic and genotypic diversity. To identify future novel therapeutic strategies we conducted an exploratory analysis of nextgeneration sequencing (NGS) of relapsed, refractory CUP. Methods: We identified patients in our phase I clinic where archival tissue was available for a targeted NGS CLIA-certified...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 28781987
DOI: 10.18632/oncoscience.352

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