Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

High mobility group A1 protein modulates autophagy in cancer cells

4 Aug 2017

Abstract excerpt

High Mobility Group A1 (HMGA1) is an architectural chromatin protein whose overexpression is a feature of malignant neoplasias with a causal role in cancer initiation and progression. HMGA1 promotes tumor growth by several mechanisms, including increase of cell proliferation and survival, impairment of DNA repair and induction of chromosome instability. Autophagy is a self-degradative process that, by providing...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to Cancer-related molecular mechanisms research
Share to Epigenetics and DNA Methylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28777374
DOI: 10.1038/cdd.2017.117

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

High mobility group A1 protein modulates autophagy in cancer cellsPMID 28777374Read ↗

The progression of HMGB1-induced autophagy in cancer biologySemantic proximity Read ↗

HMGB1 in the interplay between autophagy and apoptosis in cancerSemantic proximity Read ↗

Endogenous HMGB1 regulates autophagySemantic proximity Read ↗

HMGB1 regulates autophagy through increasing transcriptional activities of JNK and ERK in human myeloid leukemia cellsSemantic proximity Read ↗

Role of HMGB1 and its associated signaling pathways in human malignanciesSemantic proximity Read ↗

Endogenous HMGB1 regulates autophagy.Semantic proximity Read ↗

Multiple functions of HMGB1 in cancerSemantic proximity Read ↗

p53/HMGB1 Complexes Regulate Autophagy and ApoptosisSemantic proximity Read ↗

The dual role and therapeutic potential of high-mobility group box 1 in cancerSemantic proximity Read ↗

High mobility group box 1 (HMGB1): a pivotal regulator of hematopoietic malignanciesSemantic proximity Read ↗

High Mobility Group Box 1 (HMGB1): Molecular Signaling and Potential Therapeutic StrategiesSemantic proximity Read ↗

Transcriptional and epigenetic profiling of nutrient-deprived cells to identify novel regulators of autophagySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.