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Article

Quantification of transplant-derived circulating cell-free DNA in absence of a donor genotype.

PLoS computational biology - 1 Aug 2017

Sharon Eilon, Shi Hao, Kharbanda Sandhya, Koh Winston, Martin Lance R, Khush Kiran K, Valantine Hannah, Pritchard Jonathan K, De Vlaminck Iwijn

Abstract excerpt

Quantification of cell-free DNA (cfDNA) in circulating blood derived from a transplanted organ is a powerful approach to monitoring post-transplant injury. Genome transplant dynamics (GTD) quantifies donor-derived cfDNA (dd-cfDNA) by taking advantage of single-nucleotide polymorphisms (SNPs) distributed across the genome to discriminate donor and recipient DNA molecules. In its current implementation, GTD...

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Source

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Identifiers

PMID: 28771616
DOI: 10.1371/journal.pcbi.1005629
PMCID: PMC5542400

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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