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Article

Vax1 Plays an Indirect Role in the Etiology of Murine Cleft Palate.

Journal of dental research - 1 Dec 2017

Geoghegan F, Xavier G M, Birjandi A A, Seppala M, Cobourne M T

Abstract excerpt

Cleft lip with or without palate (CLP) and isolated cleft palate (CP) are common human developmental malformations with a complex etiology that reflects a failure of normal facial development. VAX1 encodes a homeobox-containing transcription factor identified as a candidate gene for CLP in human populations, with targeted deletion in mice associated with multiple anomalies, including disruption of the visual...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28771384
DOI: 10.1177/0022034517724145

Genes

VAX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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