Article
Evolution of copper arsenate resistance for enhanced enargite bioleaching using the extreme thermoacidophile Metallosphaera sedula.
Journal of industrial microbiology & biotechnology - 1 Dec 2017
Ai Chenbing, McCarthy Samuel, Liang Yuting, Rudrappa Deepak, Qiu Guanzhou, Blum Paul
Abstract excerpt
Adaptive laboratory evolution (ALE) was employed to isolate arsenate and copper cross-resistant strains, from the copper-resistant M. sedula CuR1. The evolved strains, M. sedula ARS50-1 and M. sedula ARS50-2, contained 12 and 13 additional mutations, respectively, relative to M. sedula CuR1. Bioleaching capacity of a defined consortium (consisting of a naturally occurring strain and a genetically engineered...
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