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Article

Hybrid clone cells derived from human breast epithelial cells and human breast cancer cells exhibit properties of cancer stem/initiating cells.

BMC cancer - 2 Aug 2017

Gauck Daria, Keil Silvia, Niggemann Bernd, Zänker Kurt S, Dittmar Thomas

Abstract excerpt

BACKGROUND: The biological phenomenon of cell fusion has been associated with cancer progression since it was determined that normal cell × tumor cell fusion-derived hybrid cells could exhibit novel properties, such as enhanced metastatogenic capacity or increased drug resistance, and even as a mechanism that could give rise to cancer stem/initiating cells (CS/ICs). CS/ICs have been proposed as cancer cells that...

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Identifiers

PMID: 28768501
DOI: 10.1186/s12885-017-3509-9
PMCID: PMC5541689

Genes

EGF
SOX9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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