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Article

Spontaneous formation of tumorigenic hybrids between breast cancer and multipotent stromal cells is a source of tumor heterogeneity.

The American journal of pathology - 1 Jun 2012

Rappa Germana, Mercapide Javier, Lorico Aurelio

Abstract excerpt

Breast cancer progression involves cancer cell heterogeneity, with generation of invasive/metastatic breast cancer cells within populations of nonmetastatic cells of the primary tumor. Sequential genetic mutations, epithelial-to-mesenchymal transition, interaction with local stroma, and formation...

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Source

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Identifiers

PMID: 22542847
DOI: 10.1016/j.ajpath.2012.02.020
PMCID: PMC3378856

Genes

MSC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22542847-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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