Article
Transcriptome modeling and phenotypic assays for cancer precision medicine.
Archives of pharmacal research - 1 Aug 2017
Jeong Euna, Moon Sung Ung, Song Mee, Yoon Sukjoon
Abstract excerpt
Cancer precision medicine requires clinically actionable biomarkers for patient stratification and a better prediction of clinical outcome. Although thousands of cancer-enriched mutated genes have been reported by global sequencing projects, to date, only a few oncogenic mutations have been confirmed as effective biomarkers in cancer therapies. The low frequency and varied profile (i.e., allele frequency,...
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