Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

In Vitro Isolation and Characterization of Oxazolidinone-Resistant Mycobacterium tuberculosis

1 Aug 2017

Abstract excerpt

ABSTRACT Oxazolidinones are promising candidates for the treatment of Mycobacterium tuberculosis infections. We isolated linezolid-resistant strains from H37Rv (Euro-American) and HN878 (East-Asian) strains; resistance frequencies were similar in the two strains. Mutations were identified in ribosomal protein L3 (RplC) and the 23S rRNA ( rrl ). All mutant strains were cross resistant to sutezolid; a subset was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mycobacterium research and diagnosis
Share to RNA and protein synthesis mechanisms
Share to Tuberculosis Research and Epidemiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28760892
DOI: 10.1128/aac.01296-17

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

In Vitro Isolation and Characterization of Oxazolidinone-Resistant Mycobacterium tuberculosisPMID 28760892Read ↗

Characteristic exploration of Mycobacterium tuberculosis isolated from patients with linezolid-treated multidrug-resistant tuberculosis.Semantic proximity Read ↗

Isolation and characterization of compound-resistant isolates of Mycobacterium tuberculosis.Semantic proximity Read ↗

Comparison of In Vitro Activity and MIC Distributions between the Novel Oxazolidinone Delpazolid and Linezolid against Multidrug-Resistant and Extensively Drug-Resistant Mycobacterium tuberculosis in China.Semantic proximity Read ↗

<i>In Vitro</i> efficacy comparison of linezolid, tedizolid, sutezolid and delpazolid against rapid growing Mycobacteria isolated in Beijing, ChinaSemantic proximity Read ↗

Rχ-01, a New Family of Oxazolidinones That Overcome Ribosome-Based Linezolid ResistanceSemantic proximity Read ↗

Activity of LCB01-0371, a Novel Oxazolidinone, against Mycobacterium abscessusSemantic proximity Read ↗

Novel oxazolidinones harbor potent in vitro activity against the clinical isolates of multidrug-resistant Mycobacterium tuberculosis in ChinaSemantic proximity Read ↗

Characterization of In Vitro Resistance to Linezolid in Mycobacterium abscessus.Semantic proximity Read ↗

Oxazolidinones: Mechanism of action and molecular characterization of resistance mechanisms in staphylococciSemantic proximity Read ↗

Comparative In Vitro Drug Susceptibility Study of Five Oxazolidinones Against Mycobacterium tuberculosis in Hainan, ChinaSemantic proximity Read ↗

In Vitro-Selected Linezolid-Resistant <i>Mycobacterium tuberculosis</i> MutantsSemantic proximity Read ↗

In Vitro Efficacy Comparison of Linezolid, Tedizolid, Sutezolid and Delpazolid Against Rapid Growing Mycobacteria Isolated in Beijing, ChinaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.