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Activity of LCB01-0371, a Novel Oxazolidinone, against Mycobacterium abscessus

4 Jul 2017

Abstract excerpt

ABSTRACT Mycobacterium abscessus is a highly pathogenic drug-resistant rapidly growing mycobacterium. In this study, we evaluated the in vitro , intracellular, and in vivo activities of LCB01-0371, a novel and safe oxazolidinone derivative, for the treatment of M. abscessus infection and compared its resistance to that of other oxazolidinone drugs. LCB01-0371 was effective against several M. abscessus strains in...

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PMID: 28674049
DOI: 10.1128/aac.02752-16

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