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Article

NTRK Fusions in Xanthogranuloma, a Clinicopathologic and Molecular Analysis of 23 Cases

31 Mar 2025

Abstract excerpt

Xanthogranuloma is the most common category of histiocytic neoplasia, with a range of clinical behaviors from solitary cutaneous lesions to multiple cutaneous lesions and less frequent cases with evolution to disseminated disease. Solitary lesions make up 78% to 81% of total cases. We encountered 2 consecutive index patients with solitary cutaneous xanthogranuloma with NTRK overexpression by immunostaining and...

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PMID: 40162548
DOI: 10.1097/pas.0000000000002394

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