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Article

TGFBI functions similar to periostin but is uniquely dispensable during cardiac injury.

PloS one - 1 Jan 2017

Schwanekamp Jennifer A, Lorts Angela, Sargent Michelle A, York Allen J, Grimes Kelly M, Fischesser Demetria M, Gokey Jason J, Whitsett Jeffrey A, Conway Simon J, Molkentin Jeffery D

Abstract excerpt

Extracellular matrix production and accumulation stabilize the heart under normal conditions as well as form a protective scar after myocardial infarction injury, although excessive extracellular matrix accumulation with long-standing heart disease is pathological. In the current study we investigate the role of the matricellular protein, transforming growth factor beta-induced (TGFBI), which is induced in...

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Share to Aorta
Share to Cell Adhesion Molecules

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Constriction, Pathologic

Share to Disease Progression

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Source

Open in PubMed Open full text

Identifiers

PMID: 28750100
DOI: 10.1371/journal.pone.0181945
PMCID: PMC5531541

Genes

TGFBI

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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