Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Connective tissue growth factor and cardiac fibrosis

27 Nov 2008

Abstract excerpt

Cardiac fibrosis is a major pathogenic factor in a variety of cardiovascular diseases and refers to an excessive deposition of extracellular matrix components in the heart, which leads to cardiac dysfunction and eventually overt heart failure. Evidence is accumulating for a crucial role of connective tissue growth factor (CTGF) in fibrotic processes in several tissues including the heart. CTGF orchestrates the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Connective tissue disorders research
Share to Connective Tissue Growth Factor Research
Share to Pulmonary Hypertension Research and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19040711
DOI: 10.1111/j.1748-1716.2008.01936.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Connective tissue growth factor and cardiac fibrosisPMID 19040711Read ↗

Cardiac fibrosis: Pathobiology and therapeutic targetsSemantic proximity Read ↗

The TGFβ superfamily in cardiac dysfunctionSemantic proximity Read ↗

The Role of Matrix Proteins in Cardiac PathologySemantic proximity Read ↗

The role of connective tissue growth factor, a multifunctional matricellular protein, in fibroblast biologySemantic proximity Read ↗

Molecular Interplay in Cardiac Fibrosis: Exploring the Functions of RUNX2, BMP2, and NotchSemantic proximity Read ↗

Roles of TGF-<i>β</i>Signals in Endothelial-Mesenchymal Transition during Cardiac FibrosisSemantic proximity Read ↗

The Soft- and Hard-Heartedness of Cardiac Fibroblasts: Mechanotransduction Signaling Pathways in Fibrosis of the HeartSemantic proximity Read ↗

Diverse origins and activation of fibroblasts in cardiac fibrosisSemantic proximity Read ↗

Cardiac ECM: Its Epigenetic Regulation and Role in Heart Development and RepairSemantic proximity Read ↗

The ECM as a driver of heart development and repairSemantic proximity Read ↗

The extracellular matrix modulates fibroblast phenotype and function in the infarcted myocardium.Semantic proximity Read ↗

Myocardial fibroblast–matrix interactions and potential therapeutic targetsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.