Article
Philadelphia chromosome-like acute lymphoblastic leukemia: progress in a new cancer subtype.
Clinical advances in hematology & oncology : H&O - 1 Jul 2017
Wells Julia, Jain Nitin, Konopleva Marina
Abstract excerpt
Philadelphia chromosome-like (Ph-like) acute lymphoblastic leukemia (ALL) is a newly described, high-risk subtype of B-cell ALL. It is characterized by a gene expression profile similar to that of Ph-positive ALL; however, the BCR-ABL1 fusion is not present. The World Health Organization classification of myeloid neoplasms and acute leukemia recently was updated to include the Ph-like or BCR-ABL1-like ALL subtype...
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