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Article

Coexistence of EZH2, NOTCH1, IL7R, and PHF6 Mutations in Adult T-cell Acute Lymphoblastic Leukemia.

Turkish journal of haematology : official journal of Turkish Society of Haematology - 1 Dec 2017

Zhou Xilian, Gu Yan, Han Qi, Soliman Mario, Song Chunhua, Ge Zheng

Abstract excerpt

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Topics

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Share to Carrier Proteins
Share to Enhancer of Zeste Homolog 2 Protein
Share to NOTCH1 gene
Share to Interleukin-7 Receptor alpha Subunit

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

Share to Receptor, Notch1

Share to Repressor Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 28747286
DOI: 10.4274/tjh.2017.0194
PMCID: PMC5774360

Genes

NOTCH1
PHF6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

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Research trail→

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Coexistence of EZH2, NOTCH1, IL7R, and PHF6 Mutations in Adult T-cell Acute Lymphoblastic Leukemia.PMID 28747286Read ↗

Targeted sequencing identifies associations between IL7R-JAK mutations and epigenetic modulators in T-cell acute lymphoblastic leukemia.Semantic proximity Read ↗

[The characteristics and prognostic impact of NOTCH1/FBXW7 mutation and CDKN2A/B deletion in adult T-cell acute lymphoblastic leukemia patients].Semantic proximity Read ↗

EZH2 dysregulation: Potential biomarkers predicting prognosis and guiding treatment choice in acute myeloid leukaemia.Semantic proximity Read ↗

ETV6 and NOTCH1 germline variants in adult acute leukemia.Semantic proximity Read ↗

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High incidence of Notch-1 mutations in adult patients with T-cell acute lymphoblastic leukemiaSemantic proximity Read ↗

PHF6 Mutations in Hematologic MalignanciesSemantic proximity Read ↗

Adult T-cell acute lymphoblastic leukemias with IL7R pathway mutations are slow-responders who do not benefit from allogeneic stem-cell transplantation.Semantic proximity Read ↗

PHF6 and JAK3 mutations cooperate to drive T-cell acute lymphoblastic leukemia progression.Semantic proximity Read ↗

Genetic mutational profiling analysis of T cell acute lymphoblastic leukemia reveal mutant FBXW7 as a prognostic indicator for inferior survival.Semantic proximity Read ↗

EZH2, new diagnosis and prognosis marker in acute myeloid leukemia patientsSemantic proximity Read ↗

A somatic EZH2 mutation in childhood acute myeloid leukemia.Semantic proximity Read ↗

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