Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ABCG2 c.421C>A Is Associated with Outcomes after Severe Traumatic Brain Injury.

Journal of neurotrauma - 1 Jan 2018

Adams Solomon M, Conley Yvette P, Ren Dianxu, Okonkwo David O, Puccio Ava M, Dixon C Edward, Clark Robert S B, Kochanek Patrick M, Empey Philip E

Abstract excerpt

Traumatic brain injury (TBI) is a leading cause of death with no pharmacological treatments that improve outcomes. Transporter proteins participate in TBI recovery by maintaining the central nervous system (CNS) biochemical milieu. Genetic variations in transporters that alter expression and/or function have been associated with TBI outcomes. The ATP-binding cassette transporter, ABCG2, is a uric acid (UA)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to ATP Binding Cassette Transporter, Subfamily G, Member 2
Share to Brain Injuries, Traumatic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to ABCG2 gene

Share to Neoplasm Proteins

Share to Polymorphism, Single Nucleotide

Share to Recovery of Function

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 28747144
DOI: 10.1089/neu.2017.5000
PMCID: PMC5757075

Genes

ABCG2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ABCG2 c.421C>A Is Associated with Outcomes after Severe Traumatic Brain Injury.PMID 28747144Read ↗

Influence of ATP-binding cassette polymorphisms on neurological outcome after traumatic brain injury.Semantic proximity Read ↗

ABCC8 Single Nucleotide Polymorphisms are Associated with Cerebral Edema in Severe TBI.Semantic proximity Read ↗

B-Cell Lymphoma 2 (Bcl-2) Gene Is Associated with Intracranial Hypertension after Severe Traumatic Brain Injury.Semantic proximity Read ↗

Regionally clustered ABCC8 polymorphisms in a prospective cohort predict cerebral oedema and outcome in severe traumatic brain injury.Semantic proximity Read ↗

Genetic Variation and Impact on Outcome in Traumatic Brain Injury: an Overview of Recent Discoveries.Semantic proximity Read ↗

Downstream TRPM4 Polymorphisms Are Associated with Intracranial Hypertension and Statistically Interact with ABCC8 Polymorphisms in a Prospective Cohort of Severe Traumatic Brain InjurySemantic proximity Read ↗

A genome-wide association study of outcome from traumatic brain injurySemantic proximity Read ↗

Genetic predictors of outcome following traumatic brain injury.Semantic proximity Read ↗

BCL2 genotypes: functional and neurobehavioral outcomes after severe traumatic brain injury.Semantic proximity Read ↗

Mitochondrial polymorphisms impact outcomes after severe traumatic brain injury.Semantic proximity Read ↗

Moderators of gene-outcome associations following traumatic brain injury.Semantic proximity Read ↗

Variation in Candidate Traumatic Brain Injury Biomarker Genes Are Associated with Gross Neurological Outcomes after Severe Traumatic Brain Injury.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.