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Article

Interleukin-8 gene polymorphism associated with susceptibility to non-cardia gastric carcinoma with microsatellite instability.

Journal of gastroenterology and hepatology - 1 Jul 2006

Shirai Kennosuke, Ohmiya Naoki, Taguchi Ayumu, Mabuchi Nobuyuki, Yatsuya Hiroshi, Itoh Akihiro, Hirooka Yoshiki, Niwa Yasumasa, Mori Naoyoshi, Goto Hidemi

Abstract excerpt

BACKGROUND AND AIM: Gastric carcinoma (GC) with microsatellite instability (MSI) exhibits clinicopathological characteristics distinct from microsatellite-stable (MSS) GC. Both MSI and MSS carcinomas are mostly associated with chronic gastritis infected by Helicobacter pylori (Hp). The relationship between Hp-induced inflammation and the mutator pathway of MSI remains unclear. Recently, cytokine polymorphisms...

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PMID: 16824064
DOI: 10.1111/j.1440-1746.2006.04443.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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