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Article

p38MAPK plays a critical role in induction of a pro-inflammatory phenotype of retinal Müller cells following Zika virus infection.

Antiviral research - 1 Sept 2017

Zhu Shuang, Luo Huanle, Liu Hua, Ha Yonju, Mays Elizabeth R, Lawrence Ryan E, Winkelmann Evandro, Barrett Alan D, Smith Sylvia B, Wang Min, Wang Tian, Zhang Wenbo

Abstract excerpt

Zika virus (ZIKV) infection has been associated with ocular abnormalities such as chorioretinal atrophy, optic nerve abnormalities, posterior uveitis and idiopathic maculopathy. Yet our knowledge about ZIKV infection in retinal cells and its potential contribution to retinal pathology is still very limited. Here we found that primary Müller cells, the principal glial cells in the retina, expressed a high level of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28739278
DOI: 10.1016/j.antiviral.2017.07.012
PMCID: PMC5576517

Genes

AXL
STAT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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