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Article

Prototropically Allosteric Probe for Superbly Selective DNA Analysis.

Analytical chemistry - 5 Sept 2017

Lin Fan, Zhou Yufeng, Li Qiusha, Zhou Xiaoshun, Shao Yong, Habermeyer Benoit, Wang Hui, Shi Xinghua, Xu Zhiai

Abstract excerpt

Selective nucleotide recognition for biosensor evolution requires rational probe design toward the binding-pattern-susceptible readout but without serious poison in selectivity from the context sequences. In this work, we synthesized a dual-function (trihydroxyphenyl)porphyrin (POH3) to target the abasic site (AP site) in ds-DNA using the trihydroxyphenyl substituent and the tetrapyrrole macrocycle as the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28738682
DOI: 10.1021/acs.analchem.7b02077

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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