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Article

A Method for Next-Generation Sequencing of Paired Diagnostic and Remission Samples to Detect Mitochondrial DNA Mutations Associated with Leukemia.

The Journal of molecular diagnostics : JMD - 1 Sept 2017

Pagani Ilaria S, Kok Chung H, Saunders Verity A, Van der Hoek Mark B, Heatley Susan L, Schwarer Anthony P, Hahn Christopher N, Hughes Timothy P, White Deborah L, Ross David M

Abstract excerpt

Somatic mitochondrial DNA (mtDNA) mutations have been identified in many human cancers, including leukemia. To identify somatic mutations, it is necessary to have a control tissue from the same individual for comparison. When patients with leukemia achieve remission, the remission peripheral bloo...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28732215
DOI: 10.1016/j.jmoldx.2017.05.009

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-28732215-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

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