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Article

Pediatric dilated cardiomyopathy hearts display a unique gene expression profile

19 Jul 2017

Abstract excerpt

Our previous work showed myocellular differences in pediatric and adult dilated cardiomyopathy (DCM). However, a thorough characterization of the molecular pathways involved in pediatric DCM does not exist, limiting the development of age-specific therapies. To characterize this patient population, we investigated the transcriptome profile of pediatric patients. RNA-Seq from 7 DCM and 7 nonfailing (NF) explanted...

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PMID: 28724804
DOI: 10.1172/jci.insight.94249

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